Oro-Dental Drugs, Pharmaceutics and Pharmacology: Unlocking Critical Secrets for Modern Pharmaco-Kinetics and -Dynamics in Dental Therapy and Oral Surgery

Dental Pharmacology

Abstract

To simplify, oro-dental pharmacology is the study of drugs used in the treatment of oral and dental diseases. Hence, pharmacokinetics and pharmacodynamics are two essential concepts in/for the understanding of the behavior of drugs in the body. While pharmacokinetics refers to the process by which drugs are absorbed, distributed, metabolized, and excreted from the body, pharmacodynamics refers to the study of the relationship between drug concentration and its effects on the body. The absorption of drugs in the oral cavity depends on various factors, such as the physico-chemical properties of the drug, the formulation, and the oral health status of the patient. The effectiveness of a drug in treating oral and dental diseases depends on its ability to reach the target site and produce the desired effect. Therefore, efficacy and safety of a drug depend on its pharmacodynamic properties, such as its potency, selectivity, and duration of action. And so, the understanding of pharmacokinetics and pharmacodynamics is crucial in the effective use of drugs in dental therapy and oral surgery. The appropriate selection of drugs and dosages can improve treatment outcomes and reduce the risk of adverse effects. Such would require a comprehensive understanding of the principles of drug(s) action, patient-specific factors, and the specific disease or condition being treated.